QuickView for Dihydrouracil Dehydrogenase;jsessionid=6080F4F6BD5436467EC8DFAF7C47D009;jsessionid=1AE133FA9891DB8FEBB354F2458EC0EA (gene)
- Gene Symbol:
- Dpyd
Rattus norvegicus - Full name:
- dihydropyrimidine dehydrogenase
- Synonyms:
- dihydropyrimidine dehydrogenase [NADP(+)], DHPDHase, DPD, dihydrothymine dehydrogenase, dihydrouracil dehydrogenase
- Genomic Location:
- Chr 2: 214931899-215818807
- Description:
-
catalyzes the conversion of 5,6-dihydrouracil and NADP+ to uracil, NADPH, and H+ in pyrimidine degradation
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , C. elegans , Macaca mulatta , Bos taurus , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
oxidoreductase activity, acting on NAD(P)H | NADP binding | cofactor binding | cation binding | dihydropyrimidine dehydrogenase (NADP+) activity | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor | nucleotide binding | flavin adenine dinucleotide binding | iron ion binding | coenzyme binding | catalytic activity | anion binding | iron-sulfur cluster binding | identical protein binding | ion binding | organic cyclic compound binding | protein binding | protein homodimerization activity | NADH dehydrogenase activity | FAD binding | protein dimerization activity | uracil binding | transition metal ion binding | 4 iron, 4 sulfur cluster binding | drug binding | dihydrouracil dehydrogenase (NAD+) activity | metal ion binding | heterocyclic compound binding | oxidoreductase activity, acting on the CH-CH group of donors | oxidoreductase activity | small molecule binding
GO Biological Process
response to extracellular stimulus | oxidoreductase activity, acting on NAD(P)H | response to nutrient levels | beta-alanine biosynthetic process | pyrimidine nucleoside metabolic process | response to hormone | response to drug | nucleoside catabolic process | cellular process | organic substance catabolic process | dihydropyrimidine dehydrogenase (NADP+) activity | carbohydrate derivative catabolic process | deoxyribonucleoside catabolic process | thymidine metabolic process | cellular amino acid metabolic process | catabolic process | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | pyrimidine nucleobase catabolic process | response to stimulus | thymidine catabolic process | cellular amino acid biosynthetic process | circadian rhythm | rhythmic process | cellular nitrogen compound metabolic process | cellular biosynthetic process | nucleobase-containing compound catabolic process | drug catabolic process | regulation of neurotransmitter levels | nitrogen compound metabolic process | beta-alanine metabolic process | response to lipid | nucleoside metabolic process | nucleobase-containing small molecule catabolic process | small molecule metabolic process | response to corticosteroid | response to nutrient | nucleobase-containing small molecule metabolic process | neurotransmitter metabolic process | biosynthetic process | aromatic compound catabolic process | drug metabolic process | carboxylic acid metabolic process | response to organic substance | NADH dehydrogenase activity | uracil metabolic process | metabolic process | oxidation-reduction process | nucleobase catabolic process | purine nucleobase catabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | organonitrogen compound catabolic process | uracil catabolic process | neurotransmitter biosynthetic process | pyrimidine nucleobase metabolic process | response to organic cyclic compound | organic acid metabolic process | developmental process | purine nucleobase metabolic process | carbohydrate derivative metabolic process | dihydrouracil dehydrogenase (NAD+) activity | heterocycle metabolic process | oxidoreductase activity, acting on the CH-CH group of donors | cellular metabolic process | thymine catabolic process | oxidoreductase activity | response to steroid hormone | aging | response to glucocorticoid | thymine metabolic process | pyrimidine nucleoside catabolic process
GO Cellular Component
cell | cytoplasm | cytosol | intracellular
